I feel so sad when hearing it

Fruit called and asked if she can invite colleage friend come for a talk with her at home ? 

My answer is : yes but Instinctly I felt something wrong and asked 

1. What's wrong with you? ( I should use - what happen to you ? )

She said : she break up with her boy friend - the 3rd time or more ... How can I do more to support her or comforts her .., she need a shoulder I know